Its lineage means that pomelo contains many of the same compounds as grapefruit
It might seem like a strange association, but certain statins, such as atorvastatin (Lipitor) and simvastatin (Zocor), can interact with grapefruit and grapefruit juice, raising your risk for harmful side effects
According to one review by the research team that discovered the grapefruit-statin interaction, more than 85 drugs may interact with these compounds in grapefruit
Big effect
Updated on February 24, 2024 Medically reviewed by Roxana Ehsani, RD Table of Contents Pomelo Fruit Nutrition Facts Pomelo Benefits Should Anyone Not Eat
The reason this is possible is because pomelos have a shockingly thick rind
Five years ago, Franklin pioneered the Georgia Citrus Association
4–7: Certain blood pressure medications Most types of blood pressure medicines are not Pomelo Fruit Nutrition Facts
It’s shaped like a teardrop with a green or yellow flesh and a thick, pale rind
Lipitor may negatively interact with grapefruit and certain other citrus fruits Also known as Chinese grapefruit, pummelo, and its scientific name citrus maxima; Pomelo is a large citrus fruit
Drinking excessive amounts of grapefruit (approximately 1 L/day) increased drug concentrations 250%
This interaction enhances systemic drug concentration through impaired drug
A daily glass of grapefruit juice increases blood levels of simvastatin and lovastatin by about 260% if taken at the same time (about 90% if taken 12 hours apart), and atorvastatin by about 80% (whenever taken)
The abnormal accumulation of atorvastatin, lovastatin, or simvastatin in the blood can lead to a rare but potentially serious side effect called rhabdomyolysis, a breakdown of muscle tissue that can lead to kidney failure and death
Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer
Grapefruit is known for being rich in vitamin C and fiber, while pomelo offers a good amount of vitamin C and potassium
Just a single glass of juice can reduce the production of the intestinal enzyme that regulates absorption by up to 47 per cent
Obecně platí, že na prvních příčkách najdeme právě citrusy
They are also a good source of iron, calcium, phosphorus, magnesium, and sodium
Combining grapefruit with your statin medication can cause a higher chance of more severe side effects like muscle pain, joint pain, or even rhabdomyolysis
I wish I could eat it more often but my stomach doesn't like citrus very much
Muscle pain
Both grapefruit and pomelo are citrus fruits but have many differences
The former can turn yellow-orange to pink when ripe while pomelos are yellow to pale green